Abstract: Physical education is an important part of teaching work in higher vocational colleges, which has a direct impact on the overall quality of teaching work in higher vocational colleges. Under the background of "innovation and entrepreneurship", how to cultivate students' innovation and entrepreneurship consciousness and ability in the teaching process has become a major problem faced by higher vocational colleges. But it is worth noting that some higher vocational colleges pay less attention to innovation and entrepreneurship education in physical education, and the integration level of innovation and entrepreneurship education in physical education is low, which has caused some obstacles to the overall development of students. This paper briefly introduces the importance of integrating innovation and entrepreneurship education into higher vocational physical education, analyzes the challenges faced by related work, and puts forward some integration strategies, in order to bring some help for higher vocational colleges to improve their work.